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The GREGoR Consortium is aimed at significantly increasing the proportion of Mendelian disorders with an identified genetic cause through enhanced data sharing, collaboration and an increased focus on the application of new technologies, sequencing strategies and analytical approaches.
Data Coordinating Center Website Overview
The National Human Genome Research institute funded the GREGoR Consortium in 2021. The program comprises five Research Centers (RCs) and a Data Coordinating Center (DCC). The research centers will sequence samples from patients with Mendelian conditions and develop and apply novel approaches to discover causal variants. The centers will also aim to solve “unsolved” cases for which a candidate gene was not identified by solely using whole exome sequencing. The DCC will manage data release and disseminate findings; coordinate program logistics and administrative duties, and oversee an Opportunity Fund for follow-up functional studies of discoveries made by the GREGoR Consortium research centers.
To learn more, please visit the GREGoR Consortium website .
Events
Identifying Research Priorities to Accelerate Genetic Diagnosis
April 16-17, 2024
GREGOR Pre-Application Webinar |
February 12, 2020, 12:00 - 1:30 p.m., Eastern, NHGRI hosted a pre-application webinar for the Mendelian Genomics Research Consortium funding opportunities. NHGRI staff members provided an overview of the two FOAs, the goals and objectives of the program, and the application review process.
Participation in this webinar was optional and was not required to submit an application in response to RFA-HG-20-007 or RFA-HG-20-2008.
Answers to Frequently Asked Questions will be made available.
Funding Opportunities
Active
At this time, there are no current funding opportunities.
Expired
- RFA-HG-20-007 : Mendelian Genomics Research Centers (U01 - Clinical Trial Optional)
- RFA-HG-20-008: Mendelian Genomics Data Coordinating Center (U24 Clinical Trial Not Allowed)
| Component | Principal Investigator | Institution | Title | Grant Number |
| Mendelian Genomics Coordinating Center | Susanne May | University of Washington | University of Washington (UW) Mendelian Genomics Data Coordinating Center | U24HG011746 |
| Mendelian Genomics Research Centers | Stephen Montgomery | Stanford University | Stanford Mendelian Genomics Research Center | U01HG011762 |
| Anne Luria-O’Donnell | Broad Institute | Broad Institute Mendelian Genomic Research Center | U01HG011755 | |
| Jennifer Posey | Baylor College of Medicine | Baylor College of Medicine - Mendelian Genomics Research Center | U01HG011758 | |
| Eric Vilain | University of California – Irvine | Pediatric Mendelian Genomics Research Center | U01HG011745 | |
| Chia-Lin Wei | University of Washington | University of Washington Mendelian Genomics Research Center | U01HG011744 |
Grantee Information Staff Program Directors Program Analysts